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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1992 2
1993 5
1994 9
1995 4
1996 9
1997 8
1998 1
1999 12
2000 12
2001 12
2002 19
2003 17
2004 15
2005 16
2006 20
2007 33
2008 33
2009 26
2010 41
2011 48
2012 60
2013 58
2014 64
2015 57
2016 65
2017 50
2018 60
2019 64
2020 40
2021 51
2022 33
2023 24
2024 18

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888 results

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Page 1
DDIT3 Directs a Dual Mechanism to Balance Glycolysis and Oxidative Phosphorylation during Glutamine Deprivation.
Li M, Thorne RF, Shi R, Zhang XD, Li J, Li J, Zhang Q, Wu M, Liu L. Li M, et al. Adv Sci (Weinh). 2021 Jun;8(11):e2003732. doi: 10.1002/advs.202003732. Epub 2021 Mar 27. Adv Sci (Weinh). 2021. PMID: 34105294 Free PMC article.
DDIT3 is induced during glutamine deprivation to promote glycolysis and adenosine triphosphate production via suppression of the negative glycolytic regulator TIGAR. In concert, a proportion of the DDIT3 pool translocates to the mitochondria and suppresses oxidative …
DDIT3 is induced during glutamine deprivation to promote glycolysis and adenosine triphosphate production via suppression of the nega …
Cannabidiol inhibits human glioma by induction of lethal mitophagy through activating TRPV4.
Huang T, Xu T, Wang Y, Zhou Y, Yu D, Wang Z, He L, Chen Z, Zhang Y, Davidson D, Dai Y, Hang C, Liu X, Yan C. Huang T, et al. Autophagy. 2021 Nov;17(11):3592-3606. doi: 10.1080/15548627.2021.1885203. Epub 2021 Feb 25. Autophagy. 2021. PMID: 33629929 Free PMC article.
Transcriptome analysis and other results demonstrated that ER stress and the ATF4-DDIT3-TRIB3-AKT-MTOR axis downstream of TRPV4 were involved in CBD-induced mitophagy in glioma cells. ...Given the low toxicity and high tolerability of CBD, we therefore propose CBD should b …
Transcriptome analysis and other results demonstrated that ER stress and the ATF4-DDIT3-TRIB3-AKT-MTOR axis downstream of TRPV4 were …
The FUS::DDIT3 fusion oncoprotein inhibits BAF complex targeting and activity in myxoid liposarcoma.
Zullow HJ, Sankar A, Ingram DR, Samé Guerra DD, D'Avino AR, Collings CK, Lazcano R, Wang WL, Liang Y, Qi J, Lazar AJ, Kadoch C. Zullow HJ, et al. Mol Cell. 2022 May 5;82(9):1737-1750.e8. doi: 10.1016/j.molcel.2022.03.019. Epub 2022 Apr 6. Mol Cell. 2022. PMID: 35390276 Free PMC article.
Transcription factors (TFs), including fusion oncoproteins, can bind to BAF complex surfaces to direct chromatin targeting and accessibility, often activating oncogenic gene loci. Here, we demonstrate that the FUS::DDIT3 fusion oncoprotein hallmark to myxoid liposarcoma (M …
Transcription factors (TFs), including fusion oncoproteins, can bind to BAF complex surfaces to direct chromatin targeting and accessibility …
DDIT3/CHOP and the sarcoma fusion oncoprotein FUS-DDIT3/TLS-CHOP bind cyclin-dependent kinase 2.
Bento C, Andersson MK, Aman P. Bento C, et al. BMC Cell Biol. 2009 Dec 17;10:89. doi: 10.1186/1471-2121-10-89. BMC Cell Biol. 2009. PMID: 20017906 Free PMC article.
We found that FUS-DDIT3 and the normal DDIT3 bind CDK2. In addition, CDK2 showed an increased affinity for cytoskeletal proteins in cells expressing FUS-DDIT3 and DDIT3. CONCLUSIONS: We conclude that DDIT3 binds CDK2 and that many of the observe …
We found that FUS-DDIT3 and the normal DDIT3 bind CDK2. In addition, CDK2 showed an increased affinity for cytoskeletal protei …
Gene of the month: DDIT3.
Diaz-Perez JA, Kerr DA. Diaz-Perez JA, et al. J Clin Pathol. 2024 Mar 20;77(4):211-216. doi: 10.1136/jcp-2023-208963. J Clin Pathol. 2024. PMID: 38053287 Review.
In disease, FUS/EWSR1::DDIT3 fusion is the pathogenic event that drives the development of myxoid liposarcoma. The amplification of DDIT3 in other adipocytic neoplasms mediates the presence of adipoblast-like elements. ...
In disease, FUS/EWSR1::DDIT3 fusion is the pathogenic event that drives the development of myxoid liposarcoma. The amplification of …
Inhibition of glioma growth by flavokawain B is mediated through endoplasmic reticulum stress induced autophagy.
Wang J, Qi Q, Zhou W, Feng Z, Huang B, Chen A, Zhang D, Li W, Zhang Q, Jiang Z, Bjerkvig R, Prestegarden L, Thorsen F, Wang X, Li X, Wang J. Wang J, et al. Autophagy. 2018;14(11):2007-2022. doi: 10.1080/15548627.2018.1501133. Epub 2018 Aug 17. Autophagy. 2018. PMID: 30025493 Free PMC article.
Western blot revealed that molecular components of the endoplasmic reticulum stress pathway were activated, including ATF4 (activating transcription factor 4) and DDIT3 (DNA damage inducible transcript 3), while levels of TRIB3 (tribbles pseudokinase 3) increased. ...Our r …
Western blot revealed that molecular components of the endoplasmic reticulum stress pathway were activated, including ATF4 (activating trans …
DDIT3 and KAT2A Proteins Regulate TNFRSF10A and TNFRSF10B Expression in Endoplasmic Reticulum Stress-mediated Apoptosis in Human Lung Cancer Cells.
Li T, Su L, Lei Y, Liu X, Zhang Y, Liu X. Li T, et al. J Biol Chem. 2015 Apr 24;290(17):11108-18. doi: 10.1074/jbc.M115.645333. Epub 2015 Mar 13. J Biol Chem. 2015. PMID: 25770212 Free PMC article.
We found that DDIT3 interacts with phospho-JUN, and the DDIT3.phospho-JUN complex binds to the AP-1 binding site (-304/-298) within the TNFRSF10A promoter region. ...ChIP results suggest that KAT2A may participate in a KAT2A.DDIT3.phospho-JUN complex, or may …
We found that DDIT3 interacts with phospho-JUN, and the DDIT3.phospho-JUN complex binds to the AP-1 binding site (-304/-298) w …
Epigenetic Modulation of DDIT3 and MGMT Expression Acts Synergistically with Resistance to Imatinib towards CML Disease Progression: A Hospital based Study.
Hazarika G, Kalita MJ, Kalita S, Das PP, Dutta K, Lahkar L, Rajkonwar A, Idris MG, Khamo V, Kusre G, Medhi S. Hazarika G, et al. Asian Pac J Cancer Prev. 2023 Dec 1;24(12):4059-4069. doi: 10.31557/APJCP.2023.24.12.4059. Asian Pac J Cancer Prev. 2023. PMID: 38156838 Free PMC article.
The present investigation aims to assess the role of expression analysis and methylation status of DDIT3 and MGMT genes in imatinib-resistant and nonresistant cases. ...A history of long-term alcohol consumption is found to be associated with the progression of the disease …
The present investigation aims to assess the role of expression analysis and methylation status of DDIT3 and MGMT genes in imatinib-r …
888 results